Benign and preinvasive breast lesions

res. In the following article, the most frequent benign and preinvasive lesions are depicted and their further management is explained, especially for diagnosed lesions with uncertain malignant potential. Even though current data shows a good correlation of the results of the punch biopsy and the diagnostic excision (Cipolla et al. 2006), premalignant lesions of the breast can be underestimated with histopathological techniques. Diagnostic accuracy depends on the doctor’s experience as well as on the number of acquired tissue samples (sufficient sampling). If in imaging only a high risk lesion is manifest, further advanced alterations in the adjacent tissue might have been missed out in the punch biopsy. Sometimes, incomplete removal of the lesion can lead to underestimations. In general, all inconsistent findings (discrepancy between pathological and clinical-radiological finding) by an open biopsy should be further investigated.